The Digital Infrastructures for Research 2017 (DI4R) conference will showcase policies, processes, best practices, data and services that can leverage existing initiatives to develop building blocks of the European Open Science Cloud (EOSC) and European Data Infrastructure (EDI). Topics addressed include: (1) Interoperability, (2) Data science and skills, (3) Impact evaluation and metrics, (4) Security, trust and identity, (5) The EOSC & EDI building blocks, and (6) Business models, sustainability and policies.